Clonal haematopoiesis

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United States of America Patent

PATENT NO 10683552
APP PUB NO 20170321284A1
SERIAL NO

15528807

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Abstract

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The present invention relates to clonal expansion of somatic cells in subjects, and acquired selective advantage of cell clones during the lifetime of a subject. In particular, the invention relates to methods for predicting the development of cancer based on the observation of specific genetic mutations in somatic cell clones, as well as to methods for treating or preventing cancer in a subject, in which clonal expansion of cells comprising specific modifications is observed.

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Patent Owner(s)

Patent OwnerAddress
PRESIDENT AND FELLOWS OF HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Genovese, Giulio Cambridge, US 7 28
McCarroll, Steven Andrew Cambridge, US 3 263

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