IMPROVED TREATMENTS OF CANCER RESISTANT TO TAXOIDS
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United States of America Patent
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Oct 28, 2015
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Oct 28, 2014
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The present invention relates to improved treatments of cancer resistant to a molecule of the taxoid family. It also relates to methods for selecting a patient affected with a tumor for a treatment with a molecule of the taxoid family in combination with a compound inhibiting the TGF-β signalling pathway or for determining whether a patient affected with a tumor is susceptible to benefit from a treatment with a molecule of the taxoid family in combination with a compound inhibiting the TGF-β signalling pathway as well as methods for screening or identifying a compound suitable for improving the treatment of a cancer with a molecule of the taxoid family or for reducing the resistance development during the treatment. The invention also relates to kits for performing these methods.
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