Antisense oligonucleotide for splicing adjustment of mutant dopa decarboxylase gene and using method thereof

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United States of America Patent

PATENT NO 10920225
APP PUB NO 20170321217A1
SERIAL NO

15585410

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Abstract

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This present invention discloses an antisense oligonucleotide for splicing adjustment of mutant dopa decarboxylase gene which is complementary to SEQ ID NO: 1. This antisense oligonucleotide can modulate alternative splicing site of mutant dopa decarboxylase gene. It is helpful to research and develop drug to treat AADC deficiency symptom. This present invention also discloses a method to use said antisense oligonucleotide in vitro.

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Patent OwnerAddress
TAICHUNG VETERANS GENERAL HOSPITALNO 1650 SECTION 4 TAIWAN BOULEVARD XITUN DISTRICT TAICHUNG CITY 407

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chi, Ching-Shiang Taichung, TW 1 0
Lee, Hsiu-Fen Taichung, TW 2 1
Tsai, Chi-Ren Taichung, TW 1 0

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