Polyprenylated phloroglucinol compounds as potent P-glycoprotein inducers

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United States of America Patent

PATENT NO 10202326
APP PUB NO 20170320802A1
SERIAL NO

15520063

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Abstract

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The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.

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COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHNEW DELHI 110 001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bharate, Jaideep Jammu, IN 1 1
Bharate, Sandip Jammu, IN 4 3
Joshi, Prashant Jammu, IN 47 248
Kumar, Ajay Jammu, IN 493 11870
Mudududdla, Ramesh Jammu, IN 2 1
Sharma, Rohit Jammu, IN 50 875
Vishwakarma, Ram Jammu, IN 15 19
Wani, Abubakar Jammu, IN 2 1

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