Combination Of Drugs With Protein-Binding Prodrugs
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United States of America Patent
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Issued Date -
Nov 9, 2017
app pub date -
Jul 14, 2017
filing date -
Apr 19, 2010
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Abstract
The present invention relates to a composition and a combination comprising at least one first drug and at least one protein-binding prodrug, wherein the protein-binding prodrug comprises a protein-binding group, a second drug, and a linker that can be cleaved hydrolytically, enzymatically, or in a pH-dependent manner in the body, as well as to a kit and a pharmaceutical composition comprising said composition or combination.
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