METHOD FOR SCREENING COMPOUND SPECIFICALLY SUPPRESSING FORMATION OF CAVEOLAE OF CANCER CELLS, SCREENING KIT, VECTOR AND TRANSFORMANT TO BE USED IN KIT, AND METHOD FOR SELECTING PATIENT FOR WHOM MOLECULARLY TARGETED DRUG IS INDICATED
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Sep 3, 2015
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Oct 24, 2014
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Provided is a method for screening a compound that can specifically suppress the formation of caveolae of cancer cells and can inhibit the activity of various RTKs using a single compound all at once. A method for screening a compound specifically suppressing the formation of caveolae of cancer cells wherein the screening method includes a step for bringing a test compound into contact with a system capable of detecting suppression of the binding of Cavin-1 and CAV1 and a step for selecting a compound having activity to suppress the binding of Cavin-1 and CAV1.
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