Specific expression of half-tRNA in cancers
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United States of America Patent
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May 26, 2020
Grant Date -
Nov 2, 2017
app pub date -
Feb 4, 2015
filing date -
Feb 4, 2014
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Abstract
The present invention relates to systems, devices and methods for diagnosing cancer. In various embodiments, the present invention provides a method for quantifying a 5′-htRNA; a method for quantifying a 3′-htRNA; a method for obtaining a DNA library of 5′-htRNAs and a DNA library of 5′-htRNAs obtained therefrom; and a method for obtaining a DNA library of 3′-htRNAs and a DNA library of 3′-htRNAs obtained therefrom. The invention also teaches a method for determining the presence or absence of a cancer cell in a biological sample; a method of diagnosing cancer in a subject; and a method of prognosing cancer in a subject.
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