Cellular Delivery of DNA Intercalating Agents
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United States of America Patent
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Jun 23, 2017
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Mar 21, 2013
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Abstract
Compositions and methods for targeted delivery of active agents to cells are provided. The compositions comprise a wholly or partially double-stranded synthetic DNA carrier, and an active agent intercalated in double-stranded portions of the DNA carrier. The DNA carrier may also be linked to a targeting agent. The compositions are useful for delivering an active agent into a targeted cell type, for example a cytotoxic agent.
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