PREDICTING TUMOR RESPONSES TO ANTIBODIES AGAINST HEPATOCYTE GROWTH FACTOR (HGF) AND/OR ITS COGNATE RECEPTOR, C-MET

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United States of America Patent

APP PUB NO 20170306415A1
SERIAL NO

15515889

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides methods for selecting a therapy for, or for providing a treatment to, a patient having a cancer. The methods of the present invention comprise detecting the protein biomarkers c-Met, HGF, and EpCAM in cancer cells or cancerous tissues of a subject, and predicting the subject's responsiveness to treatment with a c-Met-targeted or other HGF-inhibitory treatment, thereby enabling the selection and administration of an effective therapeutic.

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Patent Owner(s)

Patent OwnerAddress
MERRIMACK PHARMACEUTICALS INCONE BROADWAY 14TH FLOOR CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ABU-YOUSIF, Adnan Boston, US 3 8
FULGHAM, Aaron Belmont, US 1 0
HARMS, Brian Roslindale, US 44 638
MACBEATH, Gavin Wakefield, US 32 146
RIMKUNAS, Victoria Reading, US 4 1

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