Method and apparatus for diagnosing a tumor using a histogram and excluding abnormal fluorescence corresponding to DNA aneuploidy
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United States of America Patent
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Apr 28, 2020
Grant Date -
Oct 26, 2017
app pub date -
Apr 19, 2017
filing date -
Apr 26, 2016
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Abstract
An apparatus and a method for diagnosing a tumor are provided. A histogram generating section generates a histogram from a result of a measurement of fluorescence intensity of a suspension produced from a target sample. The histogram indicates a relation between the fluorescence intensity and the number of cells. A determination section detects an S phase fluorescence intensity range corresponding to S phase cells based on the fluorescence intensity corresponding to a peak of the number of cells in the histogram, detects an abnormal fluorescence intensity range corresponding to tumor cells, based on a change in the number of cells in the S phase fluorescence intensity range, and performs a diagnosis of a tumor in the target sample based on an index of the number of cells in a range defined by excluding the abnormal fluorescence intensity range from the S phase fluorescence intensity range.
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