CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR

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United States of America Patent

SERIAL NO

15645319

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Abstract

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Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

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Patent Owner(s)

Patent OwnerAddress
PHARMACYCLICS INC995 EAST ARQUES AVENUE SUNNYVALE CA 94085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goldman, Erick Concord, US 40 499
Purro, Norbert Los Gatos, US 37 455
Smyth, Mark S Foster City, US 75 1296
Wirth, David D Oak Ridge, US 35 393

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