Pyrimidinone and its derivatives inhibiting factor XIa

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United States of America Patent

PATENT NO 10717738
APP PUB NO 20170305917A1
SERIAL NO

15644655

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Abstract

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The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the characters are as defined in the description). The compounds of the general formula (I) are inhibitors of Factor XIa, so that they are useful in the prevention of and/or therapy for thromboembolic diseases.

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Patent Owner(s)

Patent OwnerAddress
ONO PHARMACEUTICAL CO LTD1-5 DOSHO-MACHI 2-CHOME CHUO-KU OSAKA-SHI OSAKA 541-8526

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barker, John Oxfordshire, GB 26 1359
Brace, Gareth Oxfordshire, GB 3 5
Courtney, Steve Oxfordshire, GB 42 638
Flanagan, Stuart Oxfordshire, GB 8 14
Gadouleau, Elise Oxfordshire, GB 7 7
Ichihara, Osamu Tokyo, JP 13 27
Imagawa, Akira Osaka, JP 15 23
Kondo, Takashi Osaka, JP 491 3762
Kouyama, Sho Osaka, JP 8 6
Nakatani, Shingo Osaka, JP 10 117
Richardson, Anthony Oxfordshire, GB 7 43
Suzuki, Ryo Osaka, JP 310 1888
Yarnold, Chris Oxfordshire, GB 8 10

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