Processes for the Preparation of Rotigotine and Intermediates Thereof
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Sep 23, 2015
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Sep 24, 2014
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The present invention provides processes for the preparation of a compound of Formula 2 or a salt thereof, wherein R1 is selected from the group consisting of H, C1-C3 alkyl, and C(0)R3; R3 is selected from the group consisting of C1-C6 alkyl, C6-C10aryl and C7-C20 arylalkyl; the carbon atom marked with “*” is racemic, enantiomerically enriched in the (R)-configuration, or enantiomerically enriched in the (S)-configuration. Also provided are intermediate compounds of the processes.
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