Probes for improved melt discrimination and multiplexing in nucleic acid assays

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United States of America Patent

PATENT NO 10612074
APP PUB NO 20170298423A1
SERIAL NO

15581067

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Abstract

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Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

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Patent Owner(s)

Patent OwnerAddress
LUMINEX CORPORATIONAUSTIN TX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arab, Nicolas Austin, US 33 66
Collins, Chuck Austin, US 7 26
Whitman, Doug Round Rock, US 19 26

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