LATS AND BREAST CANCER

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United States of America Patent

SERIAL NO

15513935

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Abstract

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The present invention relates to a method for treating breast cancer in a subject having a breast cancer of the estrogen receptor (ERα) negative type, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of the Large Tumor Suppressor Kinase (LATS). Also provided are a siRNA decreasing or silencing the expression of the Large Tumor Suppressor Kinase (LATS), and an antibody specifically binding to the Large Tumor Suppressor Kinase (LATS), for use to treat breast cancer of the estrogen receptor (ERα) negative type.

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Patent Owner(s)

Patent OwnerAddress
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCHBASEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BENTIRES-ALJ, Mohamed Kembs-Loechle, FR 9 10
BRITSCHGI, Adrian Hergiswil, CH 7 15

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