Stable Pharmaceutical Composition Of Amorphous Ticagrelor
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United States of America Patent
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Oct 19, 2017
app pub date -
Jul 1, 2016
filing date -
Apr 18, 2016
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Abstract
A pharmaceutical composition comprises amorphous ticagrelor or a pharmaceutically acceptable salt thereof, a one or more pharmaceutically acceptable excipients, and colloidal silicon dioxide. Colloidal silicon dioxide is present in intragranular and in extragranular parts of the composition. Further, a pharmaceutical composition of amorphous ticagrelor or a pharmaceutically acceptable salt thereof is used in the treatment of a disease selected from the group consisting of myocardial infarction, thrombotic stroke, transient ischaemic attack, peripheral vascular disease and angina.
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