Tamper resistant dosage form with bimodal release profile
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United States of America Patent
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Jun 29, 2017
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May 29, 2013
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Abstract
The invention relates to a pharmaceutical dosage form comprising
- (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and(ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof,wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N.
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