Compositions comprising fusion proteins useful for modulating an immune response
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United States of America Patent
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Aug 25, 2020
Grant Date -
Oct 12, 2017
app pub date -
Sep 22, 2015
filing date -
Sep 23, 2014
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Abstract
The disclosure relates to, among other things, agents that modulate the homophilic interaction between two CRACC polypeptides, methods for making such agents, and therapeutic applications in which the agents are useful. For example, the agents described herein are useful for modulating an immune response in a mammal. Also featured are screening methods for identifying additional agents capable of modulating the activation of an immune cell exposed to an antigen.
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