Use of BMP4 for thymic regeneration

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United States of America Patent

PATENT NO 10619134
APP PUB NO 20170292111A1
SERIAL NO

15499124

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Abstract

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The present disclosure describes methods to promote thymic regeneration following injury or damage to the thymus by administering to the thymus an effective amount of (1) bone morphogenetic protein 4 (BMP4), (2) thymus-derived endothelial cells that express BMP4 or (3) a combination of BMP4 and BMP4-secreting thymus-derived endothelial cells.

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Patent Owner(s)

Patent OwnerAddress
MEMORIAL SLOAN-KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK NY 10065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dudakov, Jarrod Seattle, US 7 2
Van, Den Brink Marcel New York, US 16 28
Wertheimer, Tobias Freiburg, DE 1 0

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