Methods for improving proliferation and stemness of limbal stem cells

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United States of America Patent

PATENT NO 10894945
APP PUB NO 20170283773A1
SERIAL NO

15463737

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Abstract

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Provided are methods for improving the proliferation and stemness of limbal stem cells (LSCs) by adding a Wnt inhibitor to a medium for limbal explant cultures. When human limbal explants are cultured according to the methods, Wnt/β-catenin signaling is inhibited, resulting in improvement of LSC proliferation, and improvement in the stemness of LSCs, and thus the LSCs may be obtained in high yield.

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Patent Owner(s)

Patent OwnerAddress
CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATIONSEOCHO-GU 137-701 SEOUL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chung, So-Hyang Seoul, KR 3 0
Lee, Hyun Jung Seoul, KR 76 448

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