Biohybrid for the Use Thereof in the Regeneration of Neural Tracts
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United States of America Patent
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Jun 14, 2017
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Dec 16, 2014
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Abstract
The invention relates to a biohybrid for the use thereof in the regeneration of neural tracts, comprising an implantable tubular hybrid structure which is degradable and biocompatible and characterized in that it comprises three layers of different porosity: an inner layer a), an intermediate layer b) and an outer layer c), with uninterrupted connection among them, the three layers consisting of the same porous hydrogel based on cross-linked hyaluronic acid, a biohybrid comprising the hybrid tubular structure described, which can contain a fibrous material, preferably poly-L-lactic acid, to a method for producing said tubular hybrid structure and said biohybrid, and to the use of same for regenerating neural tracts in diseases that affect the central nervous system, preferably Parkinson's disease.
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