Biohybrid for the Use Thereof in the Regeneration of Neural Tracts

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United States of America Patent

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15622853

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Abstract

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The invention relates to a biohybrid for the use thereof in the regeneration of neural tracts, comprising an implantable tubular hybrid structure which is degradable and biocompatible and characterized in that it comprises three layers of different porosity: an inner layer a), an intermediate layer b) and an outer layer c), with uninterrupted connection among them, the three layers consisting of the same porous hydrogel based on cross-linked hyaluronic acid, a biohybrid comprising the hybrid tubular structure described, which can contain a fibrous material, preferably poly-L-lactic acid, to a method for producing said tubular hybrid structure and said biohybrid, and to the use of same for regenerating neural tracts in diseases that affect the central nervous system, preferably Parkinson's disease.

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Patent Owner(s)

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UNIVERSITAT POLITECNICA DE VALENCIACAMINO DE VERA S/N VALENCIA 46022
FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL CLÍNICO SAN CARLOSC/PROFESOR MARTÍN LAGOS S/N MADRID 28040

International Classification(s)

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  • 2017 Application Filing Year
  • B29C Class
  • 6708 Applications Filed
  • 4570 Patents Issued To-Date
  • 68.13 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BARCIA, ALBACAR Juan Antonio Madrid, ES 1 0
GOMEZ, PINEDO Ulises Alfonso Madrid, ES 1 0
MARTINEZ, RAMOS Cristina Valencia, ES 1 0
MONLEON, PRADAS Manuel Valencia, ES 4 9
VALLES, LLUCH Ana Valencia, ES 2 0
VILARINO, FELTRER Guillermo Valencia, ES 1 0

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7171242103139441111201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +010020030040050060070080090010001100120013001400

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