ALTERATION OF NEURONAL GENE EXPRESSION BY SYNTHETIC piRNAs AND BY ALTERATION OF piRNA FUNCTION

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United States of America Patent

APP PUB NO 20170275622A1
SERIAL NO

15470405

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Abstract

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Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. Further provided herein are systems and methods for the identification of target sites for regulation by piRNAs.

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Patent Owner(s)

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IBIS BIOSCIENCES INC1896 RUTHERFORD RD CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chou, Danny M Carlsbad, US 2 1
Cummins, Lendell L San Diego, US 12 174
Ecker, David J Encinitas, US 200 7669
Eshoo, Mark W San Diego, US 75 1237
Michael, Todd P Carlsbad, US 5 2
Motley, Stanley T Carlsbad, US 8 15

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