Reactivation of Axon Growth and Recovery in Chronic Spinal Cord Injury

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United States of America Patent

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15400664

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Abstract

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Disclosed are methods of treating chronic nervous system diseases or injuries, e.g., chronic spinal cord injury, using Nogo receptor antagonists, including Nogo receptor-1 (NgR1) polypeptides, Nogo receptor-1 antibodies and antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, and polynucleotides. Also disclosed are methods of noninvasively monitoring axonal growth during and after treatment with an axonal growth promoting agent.

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YALE UNIVERSITYNEW HAVEN CT 06510

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  • 2017 Application Filing Year
  • A61K Class
  • 21227 Applications Filed
  • 12841 Patents Issued To-Date
  • 60.50 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

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Inventor Name Address # of filed Patents Total Citations
STRITTMATTER, Stephen M Guilford, US 31 165

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