ISOLATED ANTI-MESOTHELIN ANTIBODIES, CONJUGATES AND USES THEREOF

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United States of America Patent

APP PUB NO 20170267755A1
SERIAL NO

15461309

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Embodiments in accordance with the present disclosure include antibody binding domains that specifically bind to mesothelin. A nanobody or conjugate construct thereof can comprise the antibody binding domain comprising complementary determining region (CDR)1 of SEQ ID NO:05 or SEQ ID NO:08, CDR2 of SEQ ID NO:06 or SEQ ID NO:09, and/or CDR3 of SEQ ID NO:07 or SEQ ID NO:10. The nanobody or conjugate constructs of the nanobody can be used for diagnosis or treatment of diseases or conditions associated with overexpression of mesothelin.

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Patent Owner(s)

Patent OwnerAddress
SRI INTERNATIONAL333 RAVENSWOOD AVENUE MENLO PARK CA 94025

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Scholler, Nathalie Menlo Park, US 26 464

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