CYCLOPROPYL FUSED THIAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20170267673A1
SERIAL NO

15354877

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Abstract

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The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I:

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ALLEN, Jennifer R Newbury Park, US 57 505
AMEGADZIE, Albert Moorpark, US 29 418
BOURBEAU, Matthew P Woodland Hills, US 22 144
BROWN, James A Moorpark, US 17 214
CHEN, Jian J Camarillo, US 74 1665
CHENG, Yuan Newbury Park, US 119 2620
FROHN, Michael J Thousand Oaks, US 46 387
GUZMAN-PEREZ, Angel Belmont, US 41 230
HARRINGTON, Paul E Camarillo, US 23 202
LIU, Longbin Thousand Oaks, US 74 1475
LIU, Qingyian Camarillo, US 66 591
LOW, Jonathan D Reseda, US 31 393
MA, Vu Van Oak Park, US 33 488
MANNING, James R Pleasant Hill, US 20 47
MINATTI, Ana Elena Santa Monica, US 41 467
NGUYEN, Thomas T Newbury Park, US 39 716
NISHIMURA, Nobuko West Hills, US 58 912
NORMAN, Mark H Thousand Oaks, US 67 1528
PETTUS, Liping H Thousand Oaks, US 46 545
PICKRELL, Alexander J Westlake Village, US 38 337
QIAN, Wenyuan Thousand Oaks, US 58 271
RUMFELT, Shannon Camarillo, US 24 366
RZASA, Robert M Ventura, US 45 717
SIEGMUND, Aaron C Ventura, US 32 809
STEC, Markian M Moorpark, US 11 60
WHITE, Ryan D Somerville, US 20 70
XUE, Qiufen Thousand Oaks, US 28 378

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