Metal(loid) chalcogen nanoparticles as universal binders for medical isotopes

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United States of America Patent

PATENT NO 10688202
APP PUB NO 20170266328A1
SERIAL NO

15329876

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Abstract

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The present disclosure, among other things, provides new technologies for preparation of medical isotope labeled metal(loid) chalcogen nanoparticles for use in medical imaging and/or therapeutic applications. Provided technologies show a number of advantages as compared with previously available options for preparing and utilizing medical isotopes, including, for example, they utilize metal(loid) chalcogen nanoparticles that serve as universal binders (e.g., via covalent or non-covalent (e.g., chelate) bonds) for medical isotopes to provide medical isotope labeled metal(loid) chalcogen nanoparticles. Surprisingly, the same metal(loid) chalcogen nanoparticles may be used to bind (e.g., covalent or non-covalent e.g., chelation) bonding) a wide variety of different useful medical isotopes without the use of traditional chelating agents.

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Patent Owner(s)

Patent OwnerAddress
MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK NY 10065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grimm, Jan New York, US 92 618
Harmsen, Stefan New York, US 7 35
Kircher, Moritz F New York, US 3 29
Shaffer, Travis New York, US 1 6
Wall, Matthew A New York, US 1 6

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