METHOD FOR PRODUCING ANIMAL MODEL OF OSTEOBLASTIC BONE METASTASIS
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United States of America
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Sep 21, 2017
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Feb 28, 2017
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Feb 28, 2017
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Provided is a method for producing an animal model of osteoblastic bone metastasis. A non-human animal in which an osteoblastic lesion is formed in a wide range has been successfully produced with a probability of 100% by: administering a calcineurin inhibitor to a non-human animal; and injecting a tumor cell into an artery or a vein of the non-human animal, wherein the non-human animal and the tumor cell are in an allogeneic or xenogeneic relation.
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