METHODS FOR PRODUCING PREPARATIONS OF RECOMBINANT AAV VIRIONS SUBSTANTIALLY FREE OF EMPTY CAPSIDS

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20170260545A1
SERIAL NO

15351725

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Abstract

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Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Qu, Guang Westborough, US 26 272
Wright, John Fraser Westborough, US 31 424

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