POLYMER-DRUG CONJUGATE BASED ON A POLYISOOLEFIN-BASED COPOLYMER

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United States of America Patent

APP PUB NO 20170258970A1
SERIAL NO

15531864

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Abstract

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A polymer-drug conjugate, which can be used in medical applications such as stents, has at least one active agent conjugated through a carboxylic acid moiety to a copolymer derived from at least one isoolefin monomer and at least one copolymerizable monomer, where the copolymerizable monomer is at least one multiolefin monomer, a β-pinene monomer or a mixture thereof. Such conjugates show improved adhesion to stainless steel and a substantial decrease in burst release of paclitaxel form a drug eluting stent (DES).

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Patent Owner(s)

Patent OwnerAddress
ARLANXEO SINGAPORE PTE LTD3A INTERNATIONAL BUSINESS PARK #07-10/18 ICON@IBP TOWER B SINGAPORE 609935

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FERRARI, Lorenzo Burlington, CA 81 243
GILLIES, Elizabeth R London, CA 7 7
McEACHRAN, Matthew Sarnia, CA 1 0
SRAN, Inderpreet Brampton, CA 1 0
TRANT, John Frederick London, CA 5 0

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