Lipid sterilization method

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United States of America Patent

PATENT NO 10888631
APP PUB NO 20170258950A1
SERIAL NO

15314353

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Abstract

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The present invention relates to a method for sterilisation of phospholipid suspensions, useful in the preparation of ultrasound contrast agent precursors comprising phospholipid-stabilised perfluorobutane microbubbles. The method provides sterility assurance, without undue thermal degradation of the phospholipid. The method is also amenable to commercial scale manufacture. Also provided are methods of preparing kits and ultrasound contrast agents incorporating the sterilisation method of the invention.

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Patent Owner(s)

Patent OwnerAddress
GE HEALTHCARE ASNYCOVEIEN 2 OSLO 0401

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Henriksen, Ingrid Oslo, NO 8 33
Kvale, Svein Oslo, NO 10 27
Sontum, Per Oslo, NO 2 0
Tokerud, Ole Johannes Oslo, NO 4 1

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