DNA-peptide combination vaccine

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United States of America Patent

PATENT NO 10695420
APP PUB NO 20170258895A1
SERIAL NO

15528502

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Abstract

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The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains

    (I) the antigenic peptide, and(II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74-87 or 130-138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, whereinthe antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.

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Patent Owner(s)

Patent OwnerAddress
ANGES INCPMO TAMACHI II 4-13-3 SHIBA MINATO-KU TOKYO 1080014 ?1080014

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koriyama, Hiroshi Suita, JP 21 114
Morishita, Ryuichi Suita, JP 102 524
Nakagami, Hironori Suita, JP 34 76
Naohara, Kenji Osaka, JP 1 1
Tomioka, Hideki Ibaraki, JP 12 41

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