MEANS AND METHODS FOR PREVENTING AND/OR TREATING CARIES

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United States of America Patent

SERIAL NO

15602475

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Abstract

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The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows:

    (a) growing said microorganism to stationary phase;(b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase;(c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and(d) detecting aggregates by the occurrence of a pellet.

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Patent Owner(s)

Patent OwnerAddress
BASF SELUDWIGSHAFEN GERMANY LUDWIGSHAFEN RHINELAND-PALATINATE

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boettner, Mewes Berlin, DE 26 110
Budde, Eckhard Koln, DE 26 127
KAESLER, Bruno Cuxhaven, DE 11 104
Knöll, Rolf Laudenbach, DE 21 37
Lang, Christine Berlin, DE 57 325
Ryser, Martin Dresden, DE 8 69
Veen, Markus Altmuhldorf, DE 41 178

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