Method for determining the repair activity of non-homologous end joining
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United States of America Patent
Stats
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Jan 9, 2018
Issued Date -
N/A
app pub date -
Aug 18, 2015
filing date -
Aug 7, 2015
priority date (Note) -
In Force
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Abstract
The invention discloses a method for determining the repair activity of NHEJ. In this method, HPRT gene is mutated by using a site-directed gene mutation technology, and plasmid transfection, and 6-TG treatment are performed. By means of the method of the invention, the NHEJ repair activity level of cells can be observed by measuring the cell viability. The method can be used for screening the effects of different drugs and different genes on the NHEJ repair activity.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
SOOCHOW UNIVERSITY | NO 199 REN'AI ROAD SUZHOU INDUSTRIAL PARK SUZHOU JIANGSU 215123 |
International Classification(s)

- 2015 Application Filing Year
- C12Q Class
- 3483 Applications Filed
- 2244 Patents Issued To-Date
- 64.43 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Du, Jie | Jiangsu, CN | 79 | 446 |
# of filed Patents : 79 Total Citations : 446 | |||
Liu, Fenju | Jiangsu, CN | 2 | 0 |
# of filed Patents : 2 Total Citations : 0 | |||
Shang, Zengfu | Jiangsu, CN | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
Yu, Jiahua | Jiangsu, CN | 4 | 17 |
# of filed Patents : 4 Total Citations : 17 | |||
Zhang, Haowen | Jiangsu, CN | 11 | 3 |
# of filed Patents : 11 Total Citations : 3 | |||
Zhang, Yushuo | Jiangsu, CN | 3 | 0 |
# of filed Patents : 3 Total Citations : 0 |
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- 0 Citation Count
- C12Q Class
- 0 % this patent is cited more than
- 7 Age
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