Method for determining the repair activity of non-homologous end joining

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United States of America Patent

PATENT NO 9863933
SERIAL NO

15310491

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Abstract

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The invention discloses a method for determining the repair activity of NHEJ. In this method, HPRT gene is mutated by using a site-directed gene mutation technology, and plasmid transfection, and 6-TG treatment are performed. By means of the method of the invention, the NHEJ repair activity level of cells can be observed by measuring the cell viability. The method can be used for screening the effects of different drugs and different genes on the NHEJ repair activity.

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Patent Owner(s)

Patent OwnerAddress
SOOCHOW UNIVERSITYNO 199 REN'AI ROAD SUZHOU INDUSTRIAL PARK SUZHOU JIANGSU 215123

International Classification(s)

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  • 2015 Application Filing Year
  • C12Q Class
  • 3483 Applications Filed
  • 2244 Patents Issued To-Date
  • 64.43 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Du, Jie Jiangsu, CN 79 446
Liu, Fenju Jiangsu, CN 2 0
Shang, Zengfu Jiangsu, CN 1 0
Yu, Jiahua Jiangsu, CN 4 17
Zhang, Haowen Jiangsu, CN 11 3
Zhang, Yushuo Jiangsu, CN 3 0

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  • 0 Citation Count
  • C12Q Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3285212917835231494333601 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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