METHOD FOR DETECTING BCR-ABL INHIBITOR RESISTANCE-RELATED MUTATION AND DATA ACQUISITION METHOD FOR PREDICTING BCR-ABL INHIBITOR RESISTANCE USING THE SAME

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United States of America Patent

SERIAL NO

15519671

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Abstract

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An object of the present invention is to detect a mutation related to BCR-ABL inhibitor resistance with high accuracy for chronic myelogenous leukemia or the like. A method for detecting the mutation comprises the steps of: amplifying a region including a fusion site and a mutation site related to BCR-ABL inhibitor resistance contained in a BCR-ABL fusion gene using a biological sample collected from a subject; and genotyping of the mutation site related to BCR-ABL inhibitor resistance using nucleic acids amplified in the above step.

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Patent Owner(s)

Patent OwnerAddress
TOYO KOHAN CO LTD2-18-1 HIGASHI-GOTANDA SHINAGAWA-KU TOKYO
YAMAGUCHI UNIVERSITY1677-1 YOSHIDA YAMAGUCHI-SHI YAMAGUCHI 7538511

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ABE, Kenichi Yamaguchi, JP 101 1260
OBA, Mitsuyoshi Yamaguchi, JP 13 4
YAMANO, Hirofumi Yamaguchi, JP 14 18
YUJIRI, Toshiaki Yamaguchi, JP 2 0

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