Assay for detection of chimeric antigen receptor T cells

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United States of America Patent

PATENT NO 10871490
APP PUB NO 20170248594A1
SERIAL NO

15417292

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is directed to a detection reagent for CAR expressing cells according to general formula (1)

description='In-line Formulae' end='lead'Xn—Sm—Do description='In-line Formulae' end='tail'

    wherein X is a polypeptide comprising at least 20 amino acids of which at least two amino acids are connected by at least one disulfide groupS is a spacer comprising at least 15 carbon atomsD is a detection moietym, o are integers independently between 1 and 200n is an integer between 4 and 200with the provisio that X binds to the antigen binding domain of a chimeric antigen receptor of a cell.

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Patent Owner(s)

Patent OwnerAddress
MILTENYI BIOTEC B V & CO KGFRIEDRICH-EBERT-STRASSE 68 51429 BERGISCH GLADBACH

International Classification(s)

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  • 2017 Application Filing Year
  • G01N Class
  • 13595 Applications Filed
  • 8906 Patents Issued To-Date
  • 65.51 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Assenmacher, Mario Bergisch Gladbach, DE 24 171
Miltenyi, Stefan Bergisch Gladbach, DE 85 1166
Niemoller, Michaela Bergisch Gladbach, DE 1 0
Nolle, Volker Kurten, DE 7 10
Richter, Anne Cologne, DE 11 56

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges463132241214274211201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90100 +025050075010001250150017502000225025002750300032503500375040004250450047505000

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