PROTEASE-ACTIVATABLE BISPECIFIC PROTEINS

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United States of America Patent

SERIAL NO

15513011

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Abstract

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Described herein are protease-activatable proteins (PABPs), which, when activated, can mediate cytolysis of target cells by effector cells. Also provided are nucleic acids encoding such PABPs and methods of making and using PABPs.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE LAW DEPARTMENT THOUSAND OAKS CA 91320-1799

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baeuerle, Patrick Gauting, DE 55 676
Michaels, Mark L Encino, US 19 233
Pentony, Martin J Seattle, US 9 169
Yan, Wei Sammamish, US 216 2357

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