Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors
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United States of America Patent
Stats
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Apr 2, 2019
Grant Date -
Aug 31, 2017
app pub date -
Aug 20, 2015
filing date -
Aug 21, 2014
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are defined in claim 1, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.
First Claim
Other Claims data not available
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International Classification(s)
- 2015 Application Filing Year
- A61K Class
- 16157 Applications Filed
- 11882 Patents Issued To-Date
- 73.55 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 5 Citation Count
- A61K Class
- 58.87 % this patent is cited more than
- 6 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Oct 2, 2026 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 2, 2030 |
