Energy-providing bone-repair degradable porous scaffold, preparation method thereof, and application thereof

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United States of America Patent

PATENT NO 9855366
APP PUB NO 20170246343A1
SERIAL NO

15130361

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Abstract

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The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold through a drying method. The porous scaffold can avoid the problem of an acidic microenvironment caused by in vivo implantation of the existing biomaterial and keep the activity of an osteoblast cell, thereby improving the rate of repairing the damaged bone tissue with the energy-based biomaterial. The porous scaffold of the invention can be used as a filling material for bone repair in a surgical operation.

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Patent Owner(s)

Patent OwnerAddress
HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY430070 NO 1037 LUOYU ROAD HONGSHAN DISTRICT WUHAN CITY HUBEI PROVINCE WUHAN CITY HUBEI PROVINCE 430070

International Classification(s)

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  • 2016 Application Filing Year
  • A61L Class
  • 2975 Applications Filed
  • 2008 Patents Issued To-Date
  • 67.50 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Mingle Wuhan, CN 1 0
Liu, Haoming Wuhan, CN 8 1
Zhang, Shengmin Wuhan, CN 4 2

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges34340434111131101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 800255075100125150175200225250275300325350375400425

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