Method for evaluating mesenchymal stem cell activity, method for culturing mesenchymal stem cells, method for producing therapeutic agent for liver dysfunction, and therapeutic agent for liver dysfunction

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United States of America Patent

PATENT NO 10744159
APP PUB NO 20170246211A1
SERIAL NO

15512390

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Abstract

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A method for evaluating the activity level of mesenchymal stem cells, and a method for culturing mesenchymal stem cells using the evaluation method in the field of culturing mesenchymal stem cells for regenerative medicine, and further, a method for producing a therapeutic agent for liver dysfunction and a therapeutic agent for liver dysfunction. This method for evaluating mesenchymal stem cell activity has an assay step for assaying the amount of adenylate kinase 4 (AK4) in the mesenchymal stem cells; and a determination step for determining the activity level of the mesenchymal stem cells from the assayed amount of adenylate kinase 4.

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Patent Owner(s)

Patent OwnerAddress
YAMAGUCHI UNIVERSITYYAMAGUCHI 753-8511
SHIBUYA CORPORATIONKANAZAWA-SHI ISHIKAWA 920-8681

International Classification(s)

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujisawa, Koichi Ube, JP 80 654
Sakaida, Isao Ube, JP 5 27
Takami, Taro Ube, JP 3 0
Terai, Shuji Niigata, JP 4 2
Yamamoto, Naoki Ube, JP 377 4138
Yoneda, Kenji Kanazawa, JP 152 2248

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges13636645326377163101 - 1011 - 2021 - 3031 - 4041 - 5051 - 600100020003000400050006000700080009000100001100012000130001400015000

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