MICRORNA-132/212 FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
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Sep 22, 2015
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Sep 22, 2014
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The present relates to the use of miRNA-132/212 mimics or activators comprising a doubled stranded ribonucleic acid molecule comprising a seed region sequence of miRNA-132 or miRNA-212, a spacer, a stabilizing sequence, and a carrier for the treatment of neurodegenerative disorders, including Alzheimer's disease, Tauopathies, Amyotrophic lateral sclerosis, Parkinson's disease, frontotemporal dementia, prion's disease, mild cognitive impairment and Huntington's disease.
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