METHODS TO DETERMINE TUMOR GENE COPY NUMBER BY ANALYSIS OF CELL-FREE DNA

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United States of America Patent

SERIAL NO

15442993

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Abstract

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Methods are provided herein to improve automatic detection of copy number variation in nucleic acid samples. These methods provide improved approaches for determining baseline copy number of genetic loci within a sample, reduce variation due to features of genetic loci, sample preparation, and probe exhaustion.

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Patent Owner(s)

Patent OwnerAddress
GUARDANT HEALTH INC505 PENOBSCOT DRIVE REDWOOD CITY CA 94063

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ABDUEVA, Diana Orinda, US 27 231
CHUDOVA, Darya San Jose, US 49 255
ELTOUKHY, Helmy Atherton, US 82 1629
TALASAZ, AmirAli Menlo Park, US 111 2633

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