Acellular biologic composition and method of manufacture
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United States of America Patent
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Sep 1, 2020
Grant Date -
Aug 24, 2017
app pub date -
May 9, 2017
filing date -
Mar 6, 2015
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Abstract
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.
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