MRNA AND/OR PROTEIN OF ERCC1 ISOFORM 3 FOR USE IN DIAGNOSING A RESISTANCE AGAINST A THERAPEUTIC AGENT AND METHOD FOR DIAGNOSING A RESISTANCE AGAINST A THERAPEUTIC AGENT USING SAID MRNA AND/OR PROTEIN
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United States of America Patent
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Aug 17, 2017
app pub date -
Sep 16, 2015
filing date -
Sep 18, 2014
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Abstract
A method for diagnosing a resistance against a therapeutic agent in a patient, which includes measuring an amount of ERCC1 isoform 3 protein and/or an amount of ERCC1 isoform 3 mRNA, which present in a liquid sample or a tissue sample obtained from the patient, and comparing the measured amount to a predetermined value, wherein an amount above the predetermined value indicates resistance against said therapeutic agent.
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