METHOD FOR ENHANCING EXTRACELLULAR VESICLE PRODUCTION
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Feb 13, 2017
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Feb 11, 2016
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Abstract
A method for enhancing extracellular vesicle production is described. A peptide that induces polymer formation is incubated with a cell culture which results in enhanced EV production. The peptide penetrates the cells and subsequently polymerizes upon exposure to enzymes (e.g. phosphatase) within the cell. The cells that contain the newly formed polymers have an increased production of EVs. These EVs can be harvested using centrifugation techniques.
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