METHOD FOR ENHANCING EXTRACELLULAR VESICLE PRODUCTION

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United States of America Patent

SERIAL NO

15430821

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Abstract

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A method for enhancing extracellular vesicle production is described. A peptide that induces polymer formation is incubated with a cell culture which results in enhanced EV production. The peptide penetrates the cells and subsequently polymerizes upon exposure to enzymes (e.g. phosphatase) within the cell. The cells that contain the newly formed polymers have an increased production of EVs. These EVs can be harvested using centrifugation techniques.

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Patent Owner(s)

Patent OwnerAddress
JAPANESE FOUNDATION FOR CANCER RESEARCH8-31 ARIAKE 3-CHOME KOTO-KU TOKYO 135-8550

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  • 2017 Application Filing Year
  • C12P Class
  • 1642 Applications Filed
  • 1019 Patents Issued To-Date
  • 62.06 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsui, Hiroshi Glen Rock, US 196 2159
Shiba, Kiyotaka Tokyo, JP 25 178

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges13071049124399321101 - 1011 - 2021 - 3031 - 4041 - 5071 - 8081 - 90100 +010020030040050060070080090010001100120013001400

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