PHARMACEUTICAL COMPOSITION IN IVERMECTIN EMULGEL FOR VETERINARY USE AS A PROMOTER SYSTEM AND BIO-ADHESIVE IN ANTIPARASITIC TREATMENT, AND METHOD FOR THE PRODUCTION THEREOF
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United States of America Patent
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Aug 12, 2015
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Aug 12, 2014
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The invention relates to a pharmaceutical composition comprising: at least one antiparasitic active ingredient for providing the pharmacological therapeutic effect; an agent having bio-adhesive properties that helps to reduce the motility and reproduction of the parasites, increasing the period of time for which the product remains on the skin of the animals; an agent having permeation- or absorption-promoting properties that contributes to increasing the cutaneous permeability of the active ingredient; a surfactant agent that is absorbed in an oil-water interface, and as a result, the molecules of said surfactant agent form a kind of bridge between the polar phase (water) and the non-polar phase (oil), thereby making the transition between both phases less abrupt; an oil which will form the oily phase of the emulsion, and which will incorporate the active ingredient; and a neutralizing agent.
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