METHOD FOR PRODUCING A CAPTURE PHASE FOR THE DETECTION OF A BIOLOGICAL TARGET, AND ASSOCIATED DETECTION METHODS AND KITS
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United States of America Patent
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Aug 10, 2017
app pub date -
Aug 3, 2015
filing date -
Aug 4, 2014
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Abstract
The invention provides a novel method of preparing a capture phase for detecting and/or quantifying a target biological entity, said capture phase including a biological ligand for the biological entity, said biological ligand being covalently bonded to an amphiphilic polymer and being immobilized on a solid support, the method being characterized in that the biological ligand is immobilized on the solid support by bringing the solid support into contact with a dispersion of micelles formed by a plurality of chains of the amphiphilic polymer, said micelles carrying a plurality of molecules of the biological ligand on the surface thereof. The invention also provides corresponding capture phases and associated detection methods and kits.
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