6-aryl amino pyridone formamide compound crystal and preparation method therefor
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United States of America Patent
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Jul 17, 2018
Grant Date -
Aug 3, 2017
app pub date -
Aug 5, 2015
filing date -
Aug 5, 2014
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Abstract
The present invention provides a crystal of 6-arylamino pyridone carboxamide compound and a preparation method thereof. The crystal is obtained by dissolving 6-(2-chloro-4-iodophenylamino)-N-(2-hydroxylethyoxyl)-5-methyl-4-oxo-4,5-dihydrofuro[3,2-c]pyridin-7-carboxamide in an aprotic polar solvent and adding a second solvent thereto. The crystallization method has the advantage of simple and convenient operations, and is beneficial to an industrial production. The resulting crystal has the advantage a high purity and good stability, and is benefit to the manufacture and storage of a medicament containing the same.
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