COMPOSITIONS AND METHODS FOR TRANSIENT IMMUNE RESPONSE MODULATION DURING VACCINATION

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United States of America Patent

SERIAL NO

15514789

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Abstract

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In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogenic compositions and methods comprise at least one agent for transient immune response modulation during vaccination.

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Patent Owner(s)

Patent OwnerAddress
DUKE UNIVERSITY2812 ERWIN ROAD SUITE 406 DURHAM NC 27705

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HAYNES, Barton F Durham, US 163 638
KELSOE, Garnett Durham, US 10 27
KURAOKA, Masayuki Durham, US 3 1
LIAO, Hua-Xin Durham, US 75 236
MOODY, M Anthony Durham, US 16 10
VERKOCZY, Laurent Durham, US 3 1

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