SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND AN IMMUNE CHECKPOINT BLOCKER

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United States of America Patent

APP PUB NO 20170216403A1
SERIAL NO

15501246

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), a therapeutic antibody or fragment thereof, and an immune checkpoint blocker. The methods of the invention can be used to treat a broad range of cancer types.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139-4307

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
IRVINE, Darrell Arlington, US 21 200
MOYNIHAN, Kelly Dare Allston, US 8 60
OPEL, Cary Francis Somerville, US 4 68
WITTRUP, Karl Dane Chestnut Hill, US 43 408

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